Peptides for toxinogenesis of Clostridium perfringens type D

The Effect of Clostridium perfringens Type D Culture Filtrate on the Mouse Body Weight

Epsilon-toxin plasmids of Clostridium perfringens type D are conjugative.

Isolates of Clostridium perfringens type D produce the potent epsilon-toxin (a CDC/U.S. Department of Agriculture overlap class B select agent) and are responsible for several economically significant enterotoxemias of domestic livestock. It is well established that the epsilon-toxin structural gene, etx, occurs on large plasmids. We show here that at least two of these plasmids are conjugative...

Anti-idiotypic antibody-induced protection against Clostridium perfringens type D.

A monoclonal antibody (BALB/c mouse) with specificity for a neutralizing epitope on the epsilon-toxin produced by Clostridium perfringens type D was used to raise anti-idiotypic antibodies (anti-Id) in different strains of mice and rabbits. These were purified and used in cross-immunization studies to induce anti-(anti-idiotype). All strains of mice and rabbits immunized with BALB/c-derived ant...

Clinico-pathological findings of Clostridium perfringens type D enterotoxaemia in goats and its hemolytic activity in different erythrocytes

The present investigation was conducted to study the effects of experimental Clostridium perfringens type D enterotoxaemia in teddy goats. Clinical signs started to appear after 30 min of experimental infection like anorexia, diarrhea, dehydration, frothing and dyspnea. Gross lesions consisted of severe congestion in tissues of varying intensity with enlarged mesenteric lymph nodes while histol...

fast detection of clostridium perfringens type a,b,c and d by multiplex pcr

clostridium perfringens is a part of the microflora of soil, and many reports have revealed the widespread occurrence of this organism in raw and processed foods. c. perfringens is classified into five types (types a to e), depending upon their ability to express alpha, beta, epsilon, and iota toxins in this study, a multiplex polymerase chain reaction (pcr) assay was developed for detection of...